achievements
EVENTS
We have organized a symposium "Magnificient Seven” about a role of 5-HT7R since 2018 https://mag7.nencki.pl/ . We plan to organize the symposium as an annual meeting enabling the exchange of knowledge and being a platform to establish new collaboration in such a narrow thematic group as the 5-HT7R signaling. Participates in the conference, despite the highly specialized interests, comes from various fields of science. Our symposium consolidates among others the community of electrophysiologists, chemists as well as behaviorists which allow us for joint research at a very multidisciplinary level.
GRANTS
National Science Centre Grant OPUS 21, 2022-2026
Grant number 2021/41/B/NZ4/02603
Molecular mechanisms of 5-HT7R-mediated resilience in stress-related disorders
Principal investigator: Jakub Włodarczyk
National Science Centre Grant OPUS 19, 2021-2025
Grant number 2020/37/B/NZ5/03891
Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mechanisms of treatment-resistant depression and overcoming it.
Consortium Grant, leader: Maj Institute of Pharmacology Polish Academy of Sciences
National Science Centre Grant OPUS 19, 2021-2025
Grant number 2020/37/B/NZ4/00808
Astrocytes-regulated oligomerization state of fructose bisphosphatase 2 (FBP2) in neurons as a basic factor regulating memory formation and mitochondria function.
Consortium Grant, leader: Wroclaw Medical University
National Science Centre Grant PRELUDIUM 19, 2021-2024
Grant number 2020/37/N/NZ4/02869
A new chapter in a long story - the role of monoamine oxidases palmitoylation in chronic stress
Principal investigator: Krystian Bijata
National Science Centre Grant OPUS 17, 2020-2023
Grant number 2019/33/B/NZ7/02822
Therapeutic potential of functionally selective ligands of the 5-HT7 receptor in treatment of Major Depressive Disorder
Consortium Grant, leader: Jagiellonian University - Medical College
National Science Centre Grant SONATA 15, 2020-2023
Grant number 2019/35/D/NZ4/02042
Localization matters - 5-HT7 receptor-dependent structural plasticity in subregions of the hippocampus
Principal investigator: Monika Bijata
National Science Centre Grant SONATA BIS, 2020-2025
Grant number 2019/34/E/NZ4/00387
The role of lipid modifications of proteins in functional neuronal plasticity, learning and memory
Principal investigator: Tomasz Wójtowicz
National Science Centre Grant OPUS, 2019-2023
Grant number 2018/29/B/NZ4/01473
Changes in the structural complexity of Golgi apparatus upon neuronal activation
Principal investigator: Joanna Dzwonek
National Science Centre Grant SONATA BIS 7, 2018-2023
Grant number 2017/26/E/NZ4/00637
Small Changes - Huge Impact: The role of S-palmitoylation
and S-nitrosylation interplay in the mice model of depression
Principal investigator: Jakub Włodarczyk
Foundation for Polish Science Grant HOMING 4, 2017-2022
Serotonin-dependent mechanism of activation of extracellular matrix metalloproteinase
Principal investigator: Monika Bijata
"Serotonin-dependent trans-synaptic mechanism of extracellular matrix modifier release” was implemented as part of the Homing program, funded by the European Regional Development Fund under the Operational Programme Intelligent Development 2014 - 2020 (PO IR), Axis IV: Increasing the scientific-research potential, Measure 4.4: Enhancing the staffing potential of the R&D sector."
AWARDS
2021-12 | SCHOLARSHIP OF THE MINISTER OF EDUCATION AND SCIENCE FOR MONIKA BIJATA
Dr. Monika Bijata has been awarded a scholarship of the Minister of Education and Science for outstanding young scientists.
Dr. Bijata is conducting research on the interaction between serotonergic signalling and the extracellular matrix in synaptic plasticity.
2020-08-18 | HONORARY DISTINCTION - JERZY KONORSKI PRIZE - best article in neurobiology:
"Synaptic potentiation at basal and apical dendrites of hippocampal pyramidal neurons involves activation of a distinct set of extracellular and intracellular molecular cues"
Patrycja Brzdąk, Olga Wójcicka, Monika Zaręba-Kozioł, Daniel Minge, Christian Henneberger, Jakub Włodarczyk, Jerzy W. Mozrzymas, Tomasz Wójtowicz
Cerebral Cortex, 2019
doi:10.1093/cercor/bhx324
https://academic.oup.com/cercor/article/29/1/283/4685972
https://ptbun.org.pl/laureaci-nagrody-zespolowej-im-jerzego-konorskiego/
2018 | SILVER CROSS OF MERIT AWARDED BY PRESIDENT OF POLAND on a proposal by the President of the Polish Academy of Sciences, for special merits in aid of science
2015 | AWARD OF II DIVISION OF POLISH ACADEMY OF SCIENCES for a team led by Dr. Włodarczyk and Dr. Dziembowska for a series of scientific papers
"The role of matrix metalloproteinases in synaptic plasticity."
Jakub Włodarczyk, Magdalena Dziembowska, Michał Stawarski, Zsuzsanna Szepesi, Aleksandra Janusz, Leszek Kaczmarek
2015 | HONORABLE DISTONCTION - JERZY KONORSKI PRIZE - best article in neurobiology:
"Genetically encoded FRET-based biosensor for imaging MMP-9 activity"
Michał Stawarski, Izabela Rutkowska-Włodarczyk, André Zeug, Monika Bijata, Hubert Madej, Leszek Kaczmarek, Jakub Włodarczyk
Biomaterials, 2014
doi: 10.1016/j.biomaterials.2013.11.033
PHD DEFENCES AND HABILITATIONS
Ewa Bączyńska (PhD 2023) | "The role of 5-HT7 receptor-dependent signaling pathway in development of depressive-like behavior in mice"
supervisor: prof. Jakub Włodarczyk, auxiliary supervisor: dr. Monika Bijata
Remigiusz Worch (DSc 2022) | ""Fusion peptide of influenza virus studied in artificial membrane systems"
Anna Bartkowiak-Kaczmarek (PhD 2021) | "Changes in S-palmitoylation and S-nitrosylation of synaptic proteins in murine model of chronic stress"
supervisor: prof. Jakub Włodarczyk; auxiliary supervisor: dr. Monika Zaręba-Kozioł
Tomasz Wójtowicz (DSc 2021) | "The role of selected matrix metalloproteases subtypes in the functional plasticity of hippocampal neurons"
Matylda Roszkowska (PhD 2019) | "The role of CD44 protein in regulating dendritic spine plasticity"
supervisor: prof. Jakub Włodarczyk
Marta Magnowska (PhD 2018) | "The role of transient proteolytic activity of matrix metalloproteinase 9 (MMP-9) in synaptic plasticity"
supervisor: prof. Jakub Włodarczyk
Monika Bijata (PhD 2016) | "Serotonergic signaling and extracellular matrix interaction in synaptic plasticity"
supervisor: prof. Jakub Włodarczyk
Michał Stawarski (PhD 2014) | "The development of genetically-encoded MMP-9 activity biosensor"
supervisor: prof. Leszek Kaczmarek; auxiliary supervisor: prof. Jakub Włodarczyk